Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed
J. Clin. Invest. Vincent H.J. Leonard, et al. 118:2448 doi:10.1172/JCI35454 [
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Figure 3Infectivity of EpR- and SLAM-blind recombinant viruses. WT
green and the mutant viruses WT
green-H
543 (H
543), WT
green-H
497 (H
497), WT
green-H
482 (H
482), WT
green-H
DOUBLE (H
D), and WT
green-H
SLAMblind (H
SLAMblind) were used to infect Vero/hSLAM cells, Vero cells, or the 3 epithelial cell lines H358, HT-1376, and H441. The phase-contrast pictures of the cells were overlaid with fluorescence microscopic images. Scale bars: 100 μm.
