Clinical Research and Public HealthIn-Press PreviewHematologyImmunologyOncology
Open Access | 
10.1172/jci.insight.210272
Vorinostat for graft-versus-host disease prevention in pediatric and young adult patients with hematologic malignancies
Nicolas Parnell,1 Xiao Cao,1 Jan H. Beumer,2 Thomas M. Braun,3 Yilei Cui,4 Gary J. Fisher,4 Guoqing Hou,5 Julianne Holleran,6 Tracey Churay,7 Michelle Rozwadowski,1 Luna Heider,1 Mark T. Vander Lugt,1 Carrie L. Kitko,8 April L. Rahrig,9 Ed Peres,10 Kirsten M. Williams,11 Julie-An Talano,12 Vanessa A. Fabrizio,13 Ghada Abusin,1 Gregory A. Yanik,1 John Magenau,14 Mary Riwes,14 Marcus J. Geer,14 Sarah Anand,14 Monalisa Ghosh,14 Attaphol Pawarode,14 Kristen Votruba,15 Pavan Reddy,16 and Sung Won Choi1
1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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1Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, University of Michigan, Ann Arbor, United States of America
2Analytical Pharmacology Shared Resource, The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, United States of America
3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, United States of America
4Department of Dermatology, University of Michigan, Ann Arbor, United States of America
5Department of Internal Medicine, Division of Gastroenterology and Hepatolog, University of Michigan, Ann Arbor, United States of America
6Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, United States of America
7Department of Internal Medicine, Division of Hematology/Oncology/Blood and, University of Michigan, Ann Arbor, United States of America
8Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Vanderbilt Children’s Hospital, Nashville, United States of America
9Department of Pediatrics, Division of Pediatric Hematology/Oncology/Stem Ce, Riley Children’s Health, Indianapolis, United States of America
10Department of Internal Medicine, Division of Hematology/Oncology/Blood and, Henry Ford Health, Detroit, United States of America
11Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta,, Emory University, Atlanta, United States of America
12Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Medical College of Wisconsin, Milwaukee, United States of America
13Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood a, Children’s Hospital Colorado, Aurora, United States of America
14Rogel Cancer Center, University of Michigan, Ann Arbor, United States of America
15Department of Psychiatry, Neuropsychology Program, University of Michigan, Ann Arbor, United States of America
16Dan L. Duncan Comprehensive Cancer Center, Houston, United States of America
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Published September 24, 2026 - More info
Copyright © 2026, Parnell et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
